Pixel-based

Eufloria (formerly known as Dyson) is a real-time strategy video game developed by indie developers Alex May, Rudolf Kremers and Brian Grainger. It was named after the Dyson tree hypothesis by Freeman Dyson that a tree-like plant could grow on a comet.

It's only a 2.5D side-scrolling platform shooter, but somehow Double D managed to capture the intensity and wackiness of the Serious Sam FPSs. Hordes of well-known monsters from the 3D games and new baddies of all sizes, power-ups, secrets, it has it all. And lo and behold, the Gun Stacker system lets you combine and use multiple weapons as one massively insane superkillertool.

A demo is available on Steam.

Welcome to the Age of Wonders, once a time of magic and peace. An age swept into the ravaging gale of chaos by the arrival of a single, uninvited race: the Humans. The fragile balance that existed between the ancient races, Elves, Dwarves, Orcs and others, has changed into a struggle for power and survival in the wake of the turmoil the Humans have brought to the land. Prepare for an adventure where you will uncover wondrous ancient artifacts, awesome magical power, and the secrets of a shattered empire. Ally with the forces of light or darkness to determine the fate of the earth in the Age of Wonders!

Avadon: The Black Fortress is a single-player role-playing video game developed by Spiderweb Software. The Avadon series is set on the fictional continent of Lynaeus, which is divided between two warring factions. There is the Pact, an alliance of five nations, and the Farlands, a loose-knit group of faded empires and barbarian territories. The Pact has banded together for safety and to fend off invasion from the other lands of Lynaeus.

At first they came from the skies, and we repelled them with hired spaceships on a shoestring budget! Now they’re back, and they’re sending their ground troops to destroy our bases – thirty-ton monsters with glowing eyes and slavering jaws! And we still don’t have any money!

Laser Squad Nemesis is a multiplayer turn-based tactics video game.
Players issue orders to a squad of soldiers or aliens. Each turn, the player gives orders to their troops, previews probable effects of those orders, and submits them to the LSN server via the web interface, or through email. Orders are resolved simultaneously after both players have submitted their orders, and the consequences of the round are sent back to both players. The result of the previous turn is viewed in a real time ten-second video, with pause, slow motion and rewind (multiple turns) options.

Rage of Mages II merges the elements of role-playing and real-time strategy. Recruit stalwart allies, gather powerful weapons, and wield awesome magic as you complete important quests and train your character. You must seek out the source of an undead menace that is terrorizing the land and obtain an ancient artifact of immense power to stop the evil onslaught.

RPG that uses an RTS interface.

Russian version is called Allods 2