Yahoo. Got things to work.
Just changed the USB port I used to one directly on the motherboard and all is well. It seemed that the USB connection from my HUB was not stable. Could hear the sound of devices connecting and disconnecting when my display was getting garbled. So just changed the connection and everything worked.
Just ran X2 and left4dead, all working nicely.
Thanks for the troubleshooting. Just set mine up with some Samsung 2433BWs and had the exact same issue. Downgraded to the 175.19 drivers and uninstalled/reinstalled PowerDesk SE and I'm running in 5040x1050 just fine now.
Sweet!
Thanks for going through the trouble for me. ; )