Neon Chrome is a top-down cyberpunk shooter with roguelike elements. It takes place in Neon Chrome, an arcology (large tower) built by Neon Corp where millions of people live. The player takes control of one of the inhabitants flagged for removal. He connects to one of thousands of assets through an immersion chair to bring down the system, with a new asset for every session, from a selection of three. Each asset has a different class, such as Assassin, Cyber Psycho or Hacker, with different abilities, variations in statistics, and two types of starting weapons that are often randomized.